Baveno portal hypertension
Baveno 7 1) Portal hypertension = HVPG >5 mm hg 2) In viral & alcoholic hepatitis – CSPH = HVPG >=10 3) In PBC, CSPH likely develops at lower HVPH, due to (unmeasured) component of pre-sinusoidal PH 4) Similarly, in NASH, CSPH may develop at HVPG < 10 Reduction in HVPG secondary to Betablockers predicts clinical response! In patients undergoing TIPS, HVPG <12 affords near-complete protection from PH complications Compensated advanced chronic liver disease (cACLD) ( a.k.a cirrhosis) <10 kPa = unlikely cACLD (<1% 3-year risk of decompensation or liver-related death) >15 Kpa = highly likely cACLD Clinically significant reduction in LSM defined as either: 1) 20% reduction, such that LSM <20 Kpa 2) Or LSM <10 Kpa ...