Pancreatic stent does not provided added advantage over rectal NSAID for prevention of post-ERCP pancreatitis: First ever RCT

 DOI: 10.1097/MPA.0000000000002090


Consecutive 321 patients with native papilla,  were randomly assigned to Pancreatic stent, 50mg rectal diclofenac or stent + diclofenac at a single centre in Japan from 2014 to 2019.

Pancreaitc injection performed in nearly half of all patients!

75% of all patients were considered high risk (either F<40, difficult cannulation, pancreatic cannulation, pancreatic injection, pre-cut, pancreatic sphincteortomy, balloon sphincteroplasty, IDUS, choledochoscopy) 

Procedure time was >30 mins in half of all patients.

5 patients in total developed pancreatitis (all mild), with no difference in any of the 3 sub-groups.





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