Study: Only RCT looking at primary prophylaxis of Gastric varix with Glue, NSBB or nothing

Source: Primary prophylaxis of gastric variceal bleeding comparing cyanoacrylate injection and beta-blockers: A randomized controlled trial - Sarin et al


In a trial of 89 patients with >20 mm size of GOV2 (after eradication of EV) or IGV1, patients treated with CyA had significantly low risk of bleeding at median follow-up of 26 months (13%), compared to patients randomized to NSBB (28%) or controls (45%) 

Main criticism: Majority of patients were GOV2. Only 13 patients out of 89 had IGV1, therefore, difficult to draw conclusions at management of IGV1.

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